HRID1944961

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN(CCCC#Cc1ccc(N)cc1)C[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(O)c2[nH]c(=O)ccc12

HCID58505222

未命名化合物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)NCCCCCCCCO)c4)cc23)c1

HCID66988028

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5ccc(C#CCCCN(C)C[C@H](O[Si](C)(C)C(C)(C)C)c6ccc(O)c7[nH]c(=O)ccc67)cc5)c4)cc23)c1

HCID86675629

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in a manner analogous to that described for Intermediate 70, using Intermediate 103 in place of 8-aminooctanol. ES/MS calcd. for C54H59N6O8SSi+ 979.4. Found m/z=979.6 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-90875775481e45c8a4d834bbd30375b9
来源数据集: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08394829B2
来源说明: uspto-grants-2013_03

反应 SMILES

OCCCCCCCCN[C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:21])=[O:20])[CH:16]=[CH:17][CH:18]=1)=[O:12].[NH2:45][C:46]1[CH:51]=[CH:50][C:49]([C:52]#[C:53][CH2:54][CH2:55][CH2:56][N:57]([CH3:80])[CH2:58][C@@H:59]([C:68]2[CH:77]=[CH:76][C:75]([OH:78])=[C:74]3[C:69]=2[CH:70]=[CH:71][C:72](=[O:79])[NH:73]3)[O:60][Si:61]([C:64]([CH3:67])([CH3:66])[CH3:65])([CH3:63])[CH3:62])=[CH:48][CH:47]=1>>[Si:61]([O:60][C@H:59]([C:68]1[CH:77]=[CH:76][C:75]([OH:78])=[C:74]2[C:69]=1[CH:70]=[CH:71][C:72](=[O:79])[NH:73]2)[CH2:58][N:57]([CH3:80])[CH2:56][CH2:55][CH2:54][C:53]#[C:52][C:49]1[CH:50]=[CH:51][C:46]([NH:45][C:11]([C:13]2[CH:14]=[C:15]([S:19]([C:22]3[CH:23]=[C:24]4[C:29](=[C:30]([CH3:32])[CH:31]=3)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]4[NH:36][C:37]3[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=3)(=[O:20])=[O:21])[CH:16]=[CH:17][CH:18]=2)=[O:12])=[CH:47][CH:48]=1)([C:64]([CH3:67])([CH3:66])[CH3:65])([CH3:62])[CH3:63]