HCID 58505108, compound → HCID 86659122, compound
Reaction equation
OCCCCCCCCN[C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:21])=[O:20])[CH:16]=[CH:17][CH:18]=1)=[O:12].[NH2:45][C:46]1[CH:51]=[CH:50][C:49]([CH2:52][CH2:53][CH2:54][CH2:55][O:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH2:62][N:63]([CH2:71][C@@H:72]([C:81]2[CH:90]=[CH:89][C:88]([O:91][C:92]([O:94][C:95]([CH3:98])([CH3:97])[CH3:96])=[O:93])=[C:87]3[C:82]=2[CH:83]=[CH:84][C:85](=[O:99])[NH:86]3)[O:73][Si:74]([C:77]([CH3:80])([CH3:79])[CH3:78])([CH3:76])[CH3:75])[C:64](=[O:70])[O:65][C:66]([CH3:69])([CH3:68])[CH3:67])=[CH:48][CH:47]=1>>[C:95]([O:94][C:92]([O:91][C:88]1[CH:89]=[CH:90][C:81]([C@@H:72]([O:73][Si:74]([C:77]([CH3:80])([CH3:79])[CH3:78])([CH3:76])[CH3:75])[CH2:71][N:63]([CH2:62][CH2:61][CH2:60][CH2:59][CH2:58][CH2:57][O:56][CH2:55][CH2:54][CH2:53][CH2:52][C:49]2[CH:48]=[CH:47][C:46]([NH:45][C:11](=[O:12])[C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([S:19]([C:22]4[CH:23]=[C:24]5[C:29](=[C:30]([CH3:32])[CH:31]=4)[N:28]=[CH:27][C:26]([C:33](=[O:34])[NH2:35])=[C:25]5[NH:36][C:37]4[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=4)(=[O:20])=[O:21])[CH:14]=3)=[CH:51][CH:50]=2)[C:64](=[O:70])[O:65][C:66]([CH3:69])([CH3:68])[CH3:67])=[C:82]2[C:87]=1[NH:86][C:85](=[O:99])[CH:84]=[CH:83]2)=[O:93])([CH3:98])([CH3:97])[CH3:96]Participants
3
Procedure
The title compound was synthesized in a manner analogous to that described for Intermediate 70, using Intermediate 108 in place of 8-aminooctanol. ES/MS calcd. for C68H87N6O13SSi+ 1255.6. Found m/z=1256 (M+H)+.
Sources & evidence
- ORD record
- ord-c52927aa32d846aaa2794a643978c87c
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08394829B2
Reaction notes
Loading…