HCID 58505055, compound → HCID 86659123, compound
Reaction equation
OCCCCCCCCN[C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:21])=[O:20])[CH:16]=[CH:17][CH:18]=1)=[O:12].[NH2:45][C:46]1[CH:97]=[CH:96][C:49]([CH2:50][CH2:51][O:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][N:59]([CH2:67][C@@H:68]([C:77]2[CH:86]=[CH:85][C:84]([O:87][C:88]([O:90][C:91]([CH3:94])([CH3:93])[CH3:92])=[O:89])=[C:83]3[C:78]=2[CH:79]=[CH:80][C:81](=[O:95])[NH:82]3)[O:69][Si:70]([C:73]([CH3:76])([CH3:75])[CH3:74])([CH3:72])[CH3:71])[C:60](=[O:66])[O:61][C:62]([CH3:65])([CH3:64])[CH3:63])=[CH:48][CH:47]=1>>[C:91]([O:90][C:88]([O:87][C:84]1[CH:85]=[CH:86][C:77]([C@@H:68]([O:69][Si:70]([C:73]([CH3:76])([CH3:75])[CH3:74])([CH3:72])[CH3:71])[CH2:67][N:59]([CH2:58][CH2:57][CH2:56][CH2:55][CH2:54][CH2:53][O:52][CH2:51][CH2:50][C:49]2[CH:48]=[CH:47][C:46]([NH:45][C:11](=[O:12])[C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([S:19]([C:22]4[CH:23]=[C:24]5[C:29](=[C:30]([CH3:32])[CH:31]=4)[N:28]=[CH:27][C:26]([C:33](=[O:34])[NH2:35])=[C:25]5[NH:36][C:37]4[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=4)(=[O:20])=[O:21])[CH:14]=3)=[CH:97][CH:96]=2)[C:60](=[O:66])[O:61][C:62]([CH3:65])([CH3:64])[CH3:63])=[C:78]2[C:83]=1[NH:82][C:81](=[O:95])[CH:80]=[CH:79]2)=[O:89])([CH3:94])([CH3:93])[CH3:92]Participants
3
Procedure
The title compound was synthesized in a manner analogous to that described for Intermediate 70, using Intermediate 111 in place of 8-aminooctanol. ES/MS calcd. for C61H75N6O11SSi+ 1127.5. Found m/z=1127.7 (M+H)+.
Sources & evidence
- ORD record
- ord-f8f98cb74e6b421f80d27354158adbdf
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08394829B2
Reaction notes
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