HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66988130, compound → (R)-6-((3-((4-(5-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)-2,2,3,3-tetramethyl-4,14-dioxa-7-aza-3-silaoctadecan-18-yl)phenyl)(methyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66988130 | HCID 66988130 | — |
| Reactant | (R)-6-((3-((3-(5-((2-((tert-butyldimethylsilyl)oxy)-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)pent-1-yn-1-yl)phenyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide | HCID 86659120 | — |
| Product | (R)-6-((3-((4-(5-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)-2,2,3,3-tetramethyl-4,14-dioxa-7-aza-3-silaoctadecan-18-yl)phenyl)(methyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide | HCID 86659124 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described for Intermediate 157, using Intermediate 99 in place of Intermediate 98. ES/MS calcd. for C54H73BrN6O9SSi+ 1069.5. Found m/z=1069.7 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394829B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-7f946c7847b84b9984fc428c8747ac34 |
| Source note | uspto-grants-2013_03 |