HRID1944970

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)N(C)CCCCCC=O)c4)cc23)c1

HCID86659092

未命名化合物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)NCCCCCCNC[C@H](O[Si](C)(C)C(C)(C)C)c5ccc(O)c(NC=O)c5)c4)cc23)c1

HCID87226477

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)N(C)CCCCCCNC[C@H](O[Si](C)(C)C(C)(C)C)c5ccc(O)c(NC=O)c5)c4)cc23)c1

HCID87226531

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in a manner analogous to that described in Intermediate 167, using Intermediate 114 in place of Intermediate 113. ES/MS calcd. C47H60N6O8SSi 896.4. Found m/z=897 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-22ae99a9ec4f490b978d5564f9da67f6
来源数据集: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08394829B2
来源说明: uspto-grants-2013_03

反应 SMILES

[Si:1]([O:8][C@H:9]([C:53]1[CH:58]=[CH:57][C:56]([OH:59])=[C:55]([NH:60][CH:61]=[O:62])[CH:54]=1)[CH2:10][NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19]([C:21]1[CH:22]=[C:23]([S:27]([C:30]2[CH:31]=[C:32]3[C:37](=[C:38]([CH3:40])[CH:39]=2)[N:36]=[CH:35][C:34]([C:41]([NH2:43])=[O:42])=[C:33]3[NH:44][C:45]2[CH:50]=[CH:49][CH:48]=[C:47]([O:51][CH3:52])[CH:46]=2)(=[O:29])=[O:28])[CH:24]=[CH:25][CH:26]=1)=[O:20])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[CH3:63]OC1C=C(NC2C3C(=C(C)C=C(S(C4C=CC=C(C(=O)N(C)CCCCCC=O)C=4)(=O)=O)C=3)N=CC=2C(N)=O)C=CC=1>>[Si:1]([O:8][C@H:9]([C:53]1[CH:58]=[CH:57][C:56]([OH:59])=[C:55]([NH:60][CH:61]=[O:62])[CH:54]=1)[CH2:10][NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][N:18]([CH3:63])[C:19]([C:21]1[CH:22]=[C:23]([S:27]([C:30]2[CH:31]=[C:32]3[C:37](=[C:38]([CH3:40])[CH:39]=2)[N:36]=[CH:35][C:34]([C:41]([NH2:43])=[O:42])=[C:33]3[NH:44][C:45]2[CH:50]=[CH:49][CH:48]=[C:47]([O:51][CH3:52])[CH:46]=2)(=[O:28])=[O:29])[CH:24]=[CH:25][CH:26]=1)=[O:20])([C:4]([CH3:7])([CH3:5])[CH3:6])([CH3:2])[CH3:3]