HRID1944973

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)[Si](C)(C)OCc1cc([C@@H](O)CN)ccc1O

HCID58505193

未命名化合物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)N5CCC(NC[C@H](O[Si](C)(C)C(C)(C)C)c6ccc(O)c7[nH]c(=O)ccc67)CC5)c4)cc23)c1

HCID66988139

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)N5CCC(NC[C@H](O)c6ccc(O)c(CO[Si](C)(C)C(C)(C)C)c6)CC5)c4)cc23)c1

HCID66988921

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in a manner analogous to that described for Intermediate 150, using Intermediate 9 in place of Intermediate 2. ES/MS calcd. for C45H56N5O8SSi+ 854.4. Found m/z=854 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-65d23bd296ad4bf9a5dcaea7139c5bfa
来源数据集: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08394829B2
来源说明: uspto-grants-2013_03

反应 SMILES

[Si](O[C@H](C1C=CC(O)=C2C=1C=CC(=O)N2)CN[CH:12]1[CH2:17][CH2:16][N:15]([C:18]([C:20]2[CH:21]=[C:22]([S:26]([C:29]3[CH:30]=[C:31]4[C:36](=[C:37]([CH3:39])[CH:38]=3)[N:35]=[CH:34][C:33]([C:40]([NH2:42])=[O:41])=[C:32]4[NH:43][C:44]3[CH:49]=[CH:48][CH:47]=[C:46]([O:50][CH3:51])[CH:45]=3)(=[O:28])=[O:27])[CH:23]=[CH:24][CH:25]=2)=[O:19])[CH2:14][CH2:13]1)(C(C)(C)C)(C)C.[NH2:64][CH2:65][C@@H:66]([C:68]1[CH:73]=[CH:72][C:71]([OH:74])=[C:70]([CH2:75][O:76][Si:77]([C:80]([CH3:83])([CH3:82])[CH3:81])([CH3:79])[CH3:78])[CH:69]=1)[OH:67]>>[Si:77]([O:76][CH2:75][C:70]1[CH:69]=[C:68]([C@@H:66]([OH:67])[CH2:65][NH:64][CH:12]2[CH2:17][CH2:16][N:15]([C:18]([C:20]3[CH:21]=[C:22]([S:26]([C:29]4[CH:30]=[C:31]5[C:36](=[C:37]([CH3:39])[CH:38]=4)[N:35]=[CH:34][C:33]([C:40]([NH2:42])=[O:41])=[C:32]5[NH:43][C:44]4[CH:49]=[CH:48][CH:47]=[C:46]([O:50][CH3:51])[CH:45]=4)(=[O:27])=[O:28])[CH:23]=[CH:24][CH:25]=3)=[O:19])[CH2:14][CH2:13]2)[CH:73]=[CH:72][C:71]=1[OH:74])([C:80]([CH3:83])([CH3:82])[CH3:81])([CH3:78])[CH3:79]