Potassium Carbonate → HCID 25030339, compound

Participants

Reaction Steps

reacting the above said compound N1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-2-piperazinoacetamide of formula 7 with (E)-3-{4-(3-bromopropoxy) 3-methoxyphenyl]-1-(4-fluorophenyl)-2-propen-1-one or 3-(3-bromopropoxy)-2-phenyl-4H-4-chromenone in acetone in the presence potassium carbonate, under reflux, for a period of about 15 to about 20 hrs, followed by the removal of potassium carbonate by filtration and evaporating the solvent, under vacuum, and purifying the resultant product to obtain the desired compound of N1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-2-[4-(4-4-[(E)-3-(4-fluorophenyl)-3-oxo-1-propenyl]-2-methoxyphenoxy butyl)piperazino]acetamide or N1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-2-(4-3-[(4-oxo-3-phenyl-4H-2-chromenyl)oxy]propylpiperazino)acetamide.

Provenance & Evidence