Water → HCID 57940470, compound

HRID 1945142Notes

Reaction equation

HRID 1945142 reaction equation
C([N:4]1[CH2:10][C:9]([CH3:12])([CH3:11])[C:8](=[O:13])[N:7]([CH3:14])[C:6]2[CH:15]=[N:16][C:17]([Cl:19])=[N:18][C:5]1=2)C=C.O>O1CCOCC1>[Cl:19][C:17]1[N:16]=[CH:15][C:6]2[N:7]([CH3:14])[C:8](=[O:13])[C:9]([CH3:11])([CH3:12])[CH2:10][NH:4][C:5]=2[N:18]=1

Participants

4

Reactant 2

HCID 962WaterHCID 86621279HCID 86621279, compound

Product 1

HCID 57940470HCID 57940470, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

9-allyl-2-chloro-8,9-dihydro-5,7,7-trimethyl-5H-pyrimido[4,5-b][1,4]diazepin-6(7H)-one (1.21 g, 4.34 mmol, prepared by method C) and dichloro(2,7-dimethyl-octa-2,6-diene-1,8-yl) ruthenium (IV) (0.26 g, 0.43 mmol, prepared following Tetrahedron Letters, 1965, 47, 4187) were suspended in dioxane (10 mL) and water (30 mL) in a pressure tube. The resultant suspension was stirred at 100° C. over two nights.

Sources & evidence

ORD record
ord-2cd9444af560409da8fab100908e913f
Source dataset
uspto-grants-2013_03
Patent number
US08394952B2

Reaction notes

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