Isopropenylacetylene → 2-Isopropenyl-1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indole

Participants

Reaction Steps

This compound was prepared using the general Sonagashira conditions as described in general Example C, starting from N-(2-iodo-4-nitro-5-trifluoromethyl-phenyl)-methanesulfonamide (9.0 g, 21.9 mmol) and 2-methyl-1-buten-3-yne (6.25 mL, 65.7 mmol) to yield the title compound as a reddish-brown solid.

Provenance & Evidence