HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-iodophenyl)methanesulfonamide → 1-Chloro-2-(1-methanesulfonyl-1H-indol-2-yl)-propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-iodophenyl)methanesulfonamide | HCID 780001 | — |
| Reactant | 1-Chloro-2-methylbut-3-yn-2-ol | HCID 12423857 | — |
| Product | 1-Chloro-2-(1-methanesulfonyl-1H-indol-2-yl)-propan-2-ol | HCID 11514762 | — |
Reaction Steps
This compound was prepared using the general Sonagashira procedure as described in General Example C, from N-(2-iodo-phenyl)-methanesulfonamide (1.65 g, 5.55 mmol) and 1-chloro-2-methyl-but-3-yn-2-ol (0.79 g, 6.66 mmol) to yield a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394971B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-2a2ae87a7101449aa78abed00fcdc2e8 |
| Source note | uspto-grants-2013_03 |