Potassium Carbonate → HCID 68467890, compound

Participants

Reaction Conditions

Reaction Steps

3.81 g (27.9 mmol) of 3-isopropylphenol, 5.30 g (27.9 mmol) of 4-chloro-2-fluoro-5-nitrotoluene and 5.79 g (41.9 mmol) of potassium carbonate are stirred in 30 ml of N,N-dimethylformamide at 100° C. for 7 h and the mixture is poured onto ice, stirred at 0° C. for 15 min and then filtered. The solid is washed with water and hexane and dried under reduced pressure (4.03 g, 98.5% purity, 46.5% yield, log P (pH 2.3)=5.54).

Provenance & Evidence