反应详情

A solution of boron tribromide (1M in DCM, 2.3 ml) was slowly added to a stirred solution of the product from step (ii) (0.4 g) in DCM (20 ml) at 0° C. After 0.5 h a further 4 ml of boron tribromide solution was added and the mixture stirred for 1 h. The reaction was quenched with crushed ice and partitioned between water and DCM. The organics separated, dried, and evaporated under reduced pressure, yield 0.3 g.

1. customThe reaction was quenched with crushed ice
2. custompartitioned between water and DCM
3. customThe organics separated, dried
4. customevaporated under reduced pressure, yield 0.3 g