Ethyl bromoacetate → Ethyl 2-(4-chloro-2-methoxyphenoxy)acetate

HRID 1945194Notes

Reaction equation

Br[CH2:2][C:3]([O:5][CH2:6][CH3:7])=[O:4].[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[C:11]([O:16][CH3:17])[CH:10]=1>>[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:2][C:3]([O:5][CH2:6][CH3:7])=[O:4])=[C:11]([O:16][CH3:17])[CH:10]=1

Participants

Reactant 2

HCID 7748Ethyl bromoacetate

HCID 280504-Chloroguaiacol

Product 1

HCID 11701508Ethyl 2-(4-chloro-2-methoxyphenoxy)acetate

Procedure

The subtitle compound was prepared by the method of example 1 step (iv) using ethyl bromoacetate and 4-chloro-2-methoxyphenol Yield 2.7 g

Sources & evidence

ORD record: ord-d35a8cc215e14608b6def6ec128faa15
Source dataset: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08394986B2

Reaction notes

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