Sodium Methoxide → HCID 66995618, compound

HRID 1945216Notes

Reaction equation

HRID 1945216 reaction equation
[CH3:1][O-:2].[Na+].F[C:5]1[CH:10]=[CH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[CH:7][C:6]=1[O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>CO>[CH2:16]([O:15][C:6]1[CH:7]=[C:8]([C:11]([F:14])([F:13])[F:12])[CH:9]=[CH:10][C:5]=1[O:2][CH3:1])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 66995933HCID 66995933, compound

Product 1

HCID 66995618HCID 66995618, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of sodium methoxide in methanol (25% wt, 20 ml) and the product from step (i) (1.20 g) was heated at 100° C. for 3 h. The mixture was quenched with water (100 ml) and the solid was filtered and dried, yield 1.28 g.

Workup

  1. customThe mixture was quenched with water (100 ml)
  2. filtrationthe solid was filtered
  3. customdried

Sources & evidence

ORD record
ord-a9f0d93827474fc78aad37fb0bda675b
Source dataset
uspto-grants-2013_03
Patent number
US08394986B2

Reaction notes

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