HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoroanisole → 5-Fluoro-2-methoxybenzene-1-sulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoroanisole | HCID 9987 | — |
| Reactant | Chlorosulfonic acid | HCID 24638 | — |
| Product | 5-Fluoro-2-methoxybenzene-1-sulfonyl chloride | HCID 2783409 | — |
Reaction Steps
4-Fluoroanisole (10.0 g) was carefully added to chlorosulphonic acid (45.81 g) at 0° C. The mixture was stirred at RT for 2 h, then quenched with ice-water (500 ml) and the solid filtered and dried, yield 16.50 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394986B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-181973a51940422b819799a6dce45ca5 |
| Source note | uspto-grants-2013_03 |