1-Phenylethanol → Acetophenone

Participants

Reaction Conditions

Reaction Steps

8.9 mg (0.03 mmol) of 2-iodo-5-methylbenzenesulfonic acid prepared by Preparation Example 2, 1.48 g (2.4 mmol) of powdered Oxone (registered trademark) and 367 mg (3 mmol) of 1-phenylethanol were added to 3.75 ml of acetonitrile, and the mixture was heated at 70° C. while being stirred for one hour. The later treatment was carried out in the same way as in Example 1, and then acetophenone was obtained. The yield of the obtained acetophenone was determined and the result is shown in Table 1.

Provenance & Evidence