Sodium borohydride → 2,9-dibromo-13,13-dimethyl-11,13-dihydro-6H-indeno[1,2-b]anthracene-6,11-diol

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Reaction Steps

2,9-Dibromo-13,13-dimethyl-6H-indeno[1,2-b]anthracene-6,11(13H)-dione (20 g, 1 eq, 0.041 mol) was placed in a flask, and MeOH (150 ml) was added thereto. Then, sodium borohydride (6.2 g, 4 eq, 0.164 mol) was gradually added at 0° C., the reaction mixture was stirred for five hours, and ice water was gradually added thereto. The reaction solution was extracted with MC and recrystallized from hexane to give 2,9-dibromo-13,13-dimethyl-11,13-dihydro-6H-indeno[1,2-b]anthracene-6,11-diol (15 g, yield=78%).

Provenance & Evidence