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HRID1945715

反应详情

EQUATION

反应方程式

HRID 1945715 的结构方程式

REACTANTS

反应物

2
结构：Brc1nccc2[nH]ccc12
HCID24729217

4-Bromo-1H-pyrrolo[3,2-c]pyridine

C7H5BrN2

结构：CCC[CH2][Sn]([CH2]CCC)([CH2]CCC)[c]1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1
HCID59605536

未命名化合物

PRODUCTS

生成物

1
结构：Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(-c3nccc4[nH]ccc34)nc21
HCID59605746

未命名化合物

PROCEDURE

实验过程

2-(1-((9-Methyl-6-morpholino-2-(tributylstannyl)-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol (150 mg) was reacted with 4-bromo-5-azaindole via General Procedure G to afford 119 (20 mg) following reverse phase purification. MS (Q1) 491.2 (M)+. 1H NMR (400 MHz, MeOD) δ 8.31 (d, 1H), 7.51 (d, 1H), 7.45 (d, 1H), 7.34 (d, 1H), 4.39 (s, 4H), 4.03-3.69 (m, 10H), 3.31 (d, 5H), 3.01 (d, 2H), 2.10 (t, 2H), 2.03 (s, 2H), 1.75 (d, 2H), 1.53-1.22 (m, 4H), 1.13 (s, 6H)