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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1945770Generated: November 2, 2026

N,N-Dimethyl-1H-benzimidazol-2-amine → HCID 59605870, compound

https://huagongshe.com/reaction/1945770

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-Dimethyl-1H-benzimidazol-2-amineHCID 17846—
Reactant2-(1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-olHCID 59603426—
ProductHCID 59605870HCID 59605870—

Reaction Steps

Following General Procedure I for Buchwald coupling, 2-(1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol and N,N-dimethyl-1H-benzo[d]imidazol-2-amine were reacted to give 188. LCMS m/z: 534.3 (MH+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394796B2
Source datasetuspto-grants-2013_03
ORD IDord-fa3d749a84e74e3ea15970729591a013
Source noteuspto-grants-2013_03