HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethylbenzimidazole → HCID 49832772, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethylbenzimidazole | HCID 15807 | — |
| Reactant | HCID 87421277 | HCID 87421277 | — |
| Product | HCID 49832772 | HCID 49832772 | — |
Reaction Steps
Following General Procedure I for Buchwald coupling, racemic 1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)-3-fluoro-N,N-dimethylpiperidin-4-amine and 2-ethylbenzimidazole were reacted. The enantiomers were separated by SFC to give 227. LCMS m/z: 522.3 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394796B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-8a545e66cf3541c58813df207ce590ee |
| Source note | uspto-grants-2013_03 |