Neopentylamine → HCID 59606075, compound

HRID 1945826Notes

Reaction equation

HRID 1945826 reaction equation
[CH3:1][N:2]1[C:10]([CH:11]=O)=[N:9][C:8]2[C:3]1=[N:4][C:5]([N:19]1[C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=3[N:21]=[C:20]1[CH3:28])=[N:6][C:7]=2[N:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1.[CH3:29][C:30]([CH3:34])([CH3:33])[CH2:31][NH2:32]>>[CH3:29][C:30]([CH3:34])([CH3:33])[CH2:31][NH:32][CH2:11][C:10]1[N:2]([CH3:1])[C:3]2[C:8]([N:9]=1)=[C:7]([N:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1)[N:6]=[C:5]([N:19]1[C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=3[N:21]=[C:20]1[CH3:28])[N:4]=2

Participants

3

Reactant 2

HCID 79882NeopentylamineHCID 596054202-(2-methylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purine-8-carbaldehyde

Product 1

HCID 59606075HCID 59606075, compound

Procedure

Following General Procedure L for reductive amination, 9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purine-8-carbaldehyde and 2,2-dimethylpropan-1-amine were reacted to give 258. [M+H]+ 449.6.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-2cb8ab02ca304d55a768be6052c0ae42
Source dataset
uspto-grants-2013_03
Patent number
US08394796B2

Reaction notes

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