HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Methyloxetan-3-yl)methanamine → 1-(9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)-N-((3-methyloxetan-3-yl)methyl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Methyloxetan-3-yl)methanamine | HCID 15789550 | — |
| Reactant | 2-(2-methylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purine-8-carbaldehyde | HCID 59605420 | — |
| Product | 1-(9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)-N-((3-methyloxetan-3-yl)methyl)methanamine | HCID 59606047 | — |
Reaction Steps
Following General Procedure L for reductive amination, 9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purine-8-carbaldehyde and (3-methyloxetan-3-yl)methanamine were reacted to give 259. [M+H]+ 463.6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394796B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-05a963b24959432187dc2fcf64d4d73a |
| Source note | uspto-grants-2013_03 |