HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(Tetrahydrofuran-3-yl)methanamine → 1-(9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)-N-((tetrahydrofuran-3-yl)methyl)methanamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (Tetrahydrofuran-3-yl)methanamine | HCID 10898660 | — |
| Edukt | 4-(8-(bromomethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine | HCID 59605812 | — |
| Produkt | 1-(9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)-N-((tetrahydrofuran-3-yl)methyl)methanamine | HCID 59606034 | — |
Reaktionsschritte
4-(8-(Bromomethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine (50 mg) was reacted with (tetrahydrofuran-3-yl)methanamine via General Procedure E to give 6.9 mg of 297 following reverse phase purification. MS (Q1) 463.2 (M)+
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08394796B2 |
| Quelldatensatz | uspto-grants-2013_03 |
| ORD ID | ord-bbe246e14aca4c059c0f92f8a0101ca5 |
| Quellennotiz | uspto-grants-2013_03 |