HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylbenzimidazole → HCID 59605292, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylbenzimidazole | HCID 11984 | — |
| Reactant | HCID 86648261 | HCID 86648261 | — |
| Product | HCID 59605292 | HCID 59605292 | — |
Reaction Steps
Following General Procedure I for Buchwald coupling, 2-methylbenzimidazole and 2-(4-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperazin-1-yl)butan-1-ol were reacted. The enantiomers were separated by SFC to give 382. LCMS m/z: 520.3 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394796B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-37b0ea33b8ff4dc29dbc4a1b5cdf1bc6 |
| Source note | uspto-grants-2013_03 |