5-Amino-4-methylpentane-1,4-diol → HCID 59606139, compound

HRID 1945945Notes

Reaction equation

HRID 1945945 reaction equation
Br[CH2:2][C:3]1[N:4]([CH3:28])[C:5]2[C:10]([N:11]=1)=[C:9]([N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1)[N:8]=[C:7]([N:18]1[C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=3[N:20]=[C:19]1[CH3:27])[N:6]=2.[NH2:29][CH2:30][C:31]([CH3:37])([OH:36])[CH2:32][CH2:33][CH2:34][OH:35]>>[CH3:37][C:31]([OH:36])([CH2:30][NH:29][CH2:2][C:3]1[N:4]([CH3:28])[C:5]2[C:10]([N:11]=1)=[C:9]([N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1)[N:8]=[C:7]([N:18]1[C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=3[N:20]=[C:19]1[CH3:27])[N:6]=2)[CH2:32][CH2:33][CH2:34][OH:35]

Participants

3

Reactant 2

HCID 457912835-Amino-4-methylpentane-1,4-diolHCID 596058124-(8-(bromomethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine

Product 1

HCID 59606139HCID 59606139, compound

Procedure

Following General Procedure E for Displacement of alkyl bromide with amines, 4-(8-(bromomethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine and 5-amino-4-methylpentane-1,4-diol were reacted to give 410. [M+H]+ 495.6

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-60fc5337401741118624a3120d5c26f5
Source dataset
uspto-grants-2013_03
Patent number
US08394796B2

Reaction notes

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