2-(4-Piperidyl)-2-propanol → HCID 59605924, compound

HRID 1945956Notes

Reaction equation

HRID 1945956 reaction equation
[CH2:1]([C:3]1[O:4][C:5]2[CH:29]=[CH:28][CH:27]=[CH:26][C:6]=2[C:7]=1[C:8]1[N:16]=[C:15]2[C:11]([N:12]=[C:13]([CH:18]=O)[N:14]2[CH3:17])=[C:10]([N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)[N:9]=1)[CH3:2].[NH:30]1[CH2:35][CH2:34][CH:33]([C:36]([OH:39])([CH3:38])[CH3:37])[CH2:32][CH2:31]1>>[CH2:1]([C:3]1[O:4][C:5]2[CH:29]=[CH:28][CH:27]=[CH:26][C:6]=2[C:7]=1[C:8]1[N:16]=[C:15]2[C:11]([N:12]=[C:13]([CH2:18][N:30]3[CH2:35][CH2:34][CH:33]([C:36]([OH:39])([CH3:38])[CH3:37])[CH2:32][CH2:31]3)[N:14]2[CH3:17])=[C:10]([N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)[N:9]=1)[CH3:2]

Participants

3

Reactant 2

HCID 52003212-(4-Piperidyl)-2-propanolHCID 86648265HCID 86648265, compound

Product 1

HCID 59605924HCID 59605924, compound

Procedure

Following General Procedure L for reductive amination, 2-(2-ethylbenzofuran-3-yl)-9-methyl-6-morpholino-9H-purine-8-carbaldehyde and 2-(piperidin-4-yl)propan-2-ol were reacted to give 430. [M+H]+ 519.6

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-12a5ca269ba94ac1b4a5296812a900a0
Source dataset
uspto-grants-2013_03
Patent number
US08394796B2

Reaction notes

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