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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1945984Generated: November 1, 2026

2-tert-Butylbenzimidazole → HCID 59605319, compound

https://huagongshe.com/reaction/1945984

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-tert-ButylbenzimidazoleHCID 32366—
Reactant2-(1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-olHCID 59603426—
ProductHCID 59605319HCID 59605319—

Reaction Steps

2-(1-((2-Chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol (0.3 g) was reacted with tert-butylbenzimidazole via General Procedure I for Buchwald coupling to give 94.3 mg 462 following reverse phase purification. MS (Q1) 547.3 (M)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394796B2
Source datasetuspto-grants-2013_03
ORD IDord-ca6b2dd0fc8c48c68f3aeeecfc633e2f
Source noteuspto-grants-2013_03