HRID1946015

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID101235

Propanamide, 2-bromo-2-methyl-

C4H8BrNO

结构：Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CCNCC3)n(C)c2n1

HCID59605636

未命名化合物

PRODUCTS

生成物

结构：Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CCN(C(C)(C)C(N)=O)CC3)n(C)c2n1

HCID59605826

未命名化合物

PROCEDURE

实验过程

Following General Procedure C, 2-bromo-2-methyl-propionamide and 4-(9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-(piperidin-4-ylmethyl)-9H-purin-6-yl)morpholine were reacted to give 508. LCMS m/z: 532.2 (MH+)

WORKUP

后处理

customwere reacted

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-06bcdd4a571f43ac90cf215b62eb8b59
来源数据集: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08394796B2
来源说明: uspto-grants-2013_03

反应 SMILES

Br[C:2]([CH3:7])([CH3:6])[C:3]([NH2:5])=[O:4].[CH3:8][N:9]1[C:17]([CH2:18][CH:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)=[N:16][C:15]2[C:10]1=[N:11][C:12]([N:31]1[C:35]3[CH:36]=[CH:37][CH:38]=[CH:39][C:34]=3[N:33]=[C:32]1[CH3:40])=[N:13][C:14]=2[N:25]1[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1>>[CH3:6][C:2]([N:22]1[CH2:21][CH2:20][CH:19]([CH2:18][C:17]2[N:9]([CH3:8])[C:10]3[C:15]([N:16]=2)=[C:14]([N:25]2[CH2:30][CH2:29][O:28][CH2:27][CH2:26]2)[N:13]=[C:12]([N:31]2[C:35]4[CH:36]=[CH:37][CH:38]=[CH:39][C:34]=4[N:33]=[C:32]2[CH3:40])[N:11]=3)[CH2:24][CH2:23]1)([CH3:7])[C:3]([NH2:5])=[O:4]