HRID1946052

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21226445

未命名化合物

结构：CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CN(C(C)(C)C(=O)OC)C3)n(C)c2n1

HCID59605445

未命名化合物

PRODUCTS

生成物

结构：CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CN(C(C)(C)CO)C3)n(C)c2n1

HCID59605995

未命名化合物

PROCEDURE

实验过程

Following the procedure for 509, methyl 2-(3-((2-(2-ethyl-1H-benzo[d]imidazol-1-yl)-9-methyl-6-morpholino-9H-purin-8-yl)methyl)azetidin-1-yl)-2-methylpropanoate was reduced with lithium aluminum hydride to give 533. LCMS m/z: 253.2 (2M+H+)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9edf24463f274257ac73ca7b5fffd1c6
来源数据集: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08394796B2
来源说明: uspto-grants-2013_03

反应 SMILES

[CH2:1]([C:3]1[N:7]([C:8]2[N:16]=[C:15]3[C:11]([N:12]=[C:13]([CH2:18][CH:19]4[CH2:22][N:21]([C:23]([CH3:29])([CH3:28])[C:24](OC)=[O:25])[CH2:20]4)[N:14]3[CH3:17])=[C:10]([N:30]3[CH2:35][CH2:34][O:33][CH2:32][CH2:31]3)[N:9]=2)[C:6]2[CH:36]=[CH:37][CH:38]=[CH:39][C:5]=2[N:4]=1)[CH3:2].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:1]([C:3]1[N:7]([C:8]2[N:16]=[C:15]3[C:11]([N:12]=[C:13]([CH2:18][CH:19]4[CH2:20][N:21]([C:23]([CH3:29])([CH3:28])[CH2:24][OH:25])[CH2:22]4)[N:14]3[CH3:17])=[C:10]([N:30]3[CH2:35][CH2:34][O:33][CH2:32][CH2:31]3)[N:9]=2)[C:6]2[CH:36]=[CH:37][CH:38]=[CH:39][C:5]=2[N:4]=1)[CH3:2]