Methanol → 9-(Phenylmethyl)-1,4-dioxa-9-azadispiro[4.2.4.2]tetradecane

HRID 194627Notes

Reaction equation

HRID 194627 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9]2([CH2:10][CH2:11][C:12]3([O:13][CH2:14][CH2:15][O:16]3)[CH2:17][CH2:18]2)[CH2:19][CH:20]([I:22])[CH2:21]1.[CH3:34][OH:35].[O:23]1[C:24]2([CH2:25][CH2:26][C:27](=[O:28])[CH2:29][CH2:30]2)[O:31][CH2:32][CH2:33]1.[OH-:36].[OH-:38].[Pd+2:37]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9]2([CH2:10][CH2:11][C:12]3([O:13][CH2:14][CH2:15][O:16]3)[CH2:17][CH2:18]2)[CH2:19][CH2:20][CH2:21]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 670756349-Benzyl-11-iodo-1,4-dioxa-9-azadispiro[4.2.4.2]tetradecane

Product 1

HCID 670751869-(Phenylmethyl)-1,4-dioxa-9-azadispiro[4.2.4.2]tetradecane

Sources & evidence

ORD record
ord-26ca5d8d51fd46649011d5b169210a45
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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