Hydrochloric Acid → HCID 46829883, compound

Participants

Reaction Steps

Intermediate 47 (330 mg) was dissolved in methanol (3 mL) and 2M sodium hydroxide (2.42 mL) was added and the mixture stirred overnight. The mixture was blown down by ca 50% and the pH adjusted to 6 by addition of 2M hydrochloric acid. The precipitate was collected by filtration, washed with water and dried in vacuo to provide the title compound (100 mg) LC/MS MH+ 381, Rt 2.03 mins (5 min run, TFA modifier).

Provenance & Evidence