HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67007739, compound → HCID 67007812, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67007739 | HCID 67007739 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 67007812 | HCID 67007812 | 216.6% |
Reaction Steps
Title compound 207 (0.32 g, 0.878 mmol) and Pd/C (0.093 g, 0.088 mmol) were combined in methanol (16.73 mL) and formic acid (0.836 mL). The reaction mixture was stirred at reflux for 2 h. The mixture was filtered and concentrated to afford title compound 208 (0.278 g, 99%) as a clear oil. LRMS: (calc) 246.14 (found) 247.3 (MH)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399452B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-b1372d1abd4245819741d30358300307 |
| Source note | uspto-grants-2013_03 |