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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1946706Generated: October 31, 2026

4-Aminophenol → 6-(cyclopentylamino)-N-(4-hydroxyphenyl)pyrimidine-4-carboxamide

https://huagongshe.com/reaction/1946706

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminophenolHCID 403—
Reactant6-(Cyclopentylamino)pyrimidine-4-carboxylic acidHCID 59447055—
SolventAcetonitrileHCID 6342—
Product6-(cyclopentylamino)-N-(4-hydroxyphenyl)pyrimidine-4-carboxamideHCID 25182623—

Reaction Steps

Following the general method as outlined in Example 1, starting from 6-[(cyclopentyl)amino]pyrimidine-4-carboxylic acid (Intermediate 5) and 4-aminophenol (Aldrich), the title compound was obtained as a yellow solid after trituration in acetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399448B2
Source datasetuspto-grants-2013_03
ORD IDord-eaaeb7fa30d441efb8faf1b9d17cebb4
Source noteuspto-grants-2013_03