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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1946707Generated: November 2, 2026

5-Amino-2-hydroxytoluene → 6-(cyclohexylamino)-N-(4-hydroxy-3-methylphenyl)pyrimidine-4-carboxamide

https://huagongshe.com/reaction/1946707

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-2-hydroxytolueneHCID 76081—
Reactant6-(Cyclohexylamino)pyrimidine-4-carboxylic acidHCID 59447075—
Product6-(cyclohexylamino)-N-(4-hydroxy-3-methylphenyl)pyrimidine-4-carboxamideHCID 25182624—

Reaction Steps

Following the general method as outlined in Example 1, starting from 6-(cyclohexylamino)pyrimidine-4-carboxylic acid (Intermediate 4) and 4-amino-o-cresol (Aldrich), the title compound was obtained as a brown solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399448B2
Source datasetuspto-grants-2013_03
ORD IDord-ce6356080b2241f2ae2c0f5d8bba7299
Source noteuspto-grants-2013_03