HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxyxylidine → 6-(cyclohexylamino)-N-(4-hydroxy-2,3-dimethylphenyl)pyrimidine-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxyxylidine | HCID 76542 | — |
| Reactant | 6-(Cyclohexylamino)pyrimidine-4-carboxylic acid | HCID 59447075 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 6-(cyclohexylamino)-N-(4-hydroxy-2,3-dimethylphenyl)pyrimidine-4-carboxamide | HCID 25182747 | — |
Reaction Steps
Following the general method as outlined in Example 1, starting from 6-(cyclohexylamino)pyrimidine-4-carboxylic acid (Intermediate 4) and 4-amino-2,3-xylenol (TCI), the title compound was obtained as a white solid after trituration in dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399448B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-4f34289f31354b61b4c40f4c6d0908de |
| Source note | uspto-grants-2013_03 |