Dipropylamine → HCID 46880801, compound

HRID 1946724Notes

Reaction equation

HRID 1946724 reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([C:8]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][C:12]=2C)=[O:9])[CH:3]=1.[CH2:19]([NH:22][CH2:23][CH2:24][CH3:25])[CH2:20][CH3:21]>>[CH2:19]([N:22]([CH2:23][CH2:24][CH3:25])[C:2]1[N:7]=[CH:6][N:5]=[C:4]([C:8]([NH:10][C:11]2[CH:12]=[CH:13][C:14]([OH:17])=[CH:15][CH:16]=2)=[O:9])[CH:3]=1)[CH2:20][CH3:21]

Participants

3

Procedure

Following the general method as outlined in Example 20, starting from 6-chloro-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide (Intermediate 7) and dipropylamine (Aldrich), the title compound was obtained as a brown solid.

Sources & evidence

ORD record
ord-03542a0cee7c4ee0af9089677f909c0a
Source dataset
uspto-grants-2013_03
Patent number
US08399448B2

Reaction notes

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