HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfanilamide → N-[4-(aminosulfonyl)phenyl]-6-[cyclohexyl(methyl)amino]pyrimidine-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfanilamide | HCID 5333 | — |
| Reactant | 6-[Cyclohexyl(methyl)amino]pyrimidine-4-carboxylic acid | HCID 59447077 | — |
| Product | N-[4-(aminosulfonyl)phenyl]-6-[cyclohexyl(methyl)amino]pyrimidine-4-carboxamide | HCID 25182768 | — |
Reaction Steps
Following the general method as outlined in Example 1, starting from 6-[cyclohexyl(methyl)amino]pyrimidine-4-carboxylic acid (Intermediate 10) and 4-amino-benzenesulfonamide (Acros), the title compound was obtained as a pale brown solid after purification by preparative HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399448B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-c9633e18324a442c938dec1cc19b365f |
| Source note | uspto-grants-2013_03 |