HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-N-ethylbenzenesulfonamide → 6-[cyclohexyl(methyl)amino]-N-{4-[(ethylamino)sulfonyl]phenyl}pyrimidine-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-N-ethylbenzenesulfonamide | HCID 593572 | — |
| Reactant | 6-[Cyclohexyl(methyl)amino]pyrimidine-4-carboxylic acid | HCID 59447077 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-[cyclohexyl(methyl)amino]-N-{4-[(ethylamino)sulfonyl]phenyl}pyrimidine-4-carboxamide | HCID 59446879 | — |
Reaction Steps
Following the general method as outlined in Example 1, starting from 6-[cyclohexyl(methyl)amino]pyrimidine-4-carboxylic acid (Intermediate 10) and 4-amino-N-ethyl-benzenesulfonamide (Oakwood), the title compound was obtained as a white solid after trituration in methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399448B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-b048cfce54be44bfb789c0663745c58f |
| Source note | uspto-grants-2013_03 |