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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1946770Generated: November 2, 2026

Methyl 3-aminopropanoate hydrochloride → HCID 25182920, compound

https://huagongshe.com/reaction/1946770

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-aminopropanoate hydrochlorideHCID 2734767—
Reactant6-[cyclohexyl(cyclopropylmethyl)amino]-N-(4-formylphenyl)pyrimidine-4-carboxamideHCID 59446846—
ProductHCID 25182920HCID 25182920—

Reaction Steps

Following the general method as outlined in Example 73, starting from 6-[cyclohexyl(cyclopropylmethyl)amino]-N-(4-formylphenyl)pyrimidine-4-carboxamide (Intermediate 24) and beta-alanine methyl ester hydrochloride (Fluka), the title compound was obtained as a white solid after purification by column chromatography (silica) eluting with cyclohexane containing increasing amounts of EtOAc.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399448B2
Source datasetuspto-grants-2013_03
ORD IDord-46cae5b13e4d4fbcad4cff24c7070b53
Source noteuspto-grants-2013_03