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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1946775Generated: November 1, 2026

3-azetidinecarboxylic Acid → HCID 25182928, compound

https://huagongshe.com/reaction/1946775

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-azetidinecarboxylic AcidHCID 93192—
Reactant6-[cyclohexyl(cyclopropylmethyl)amino]-N-(4-formylphenyl)pyrimidine-4-carboxamideHCID 59446846—
ProductHCID 25182928HCID 25182928—

Reaction Steps

Following the general method as outlined in Example 73, starting from 6-[cyclohexyl(cyclopropylmethyl)amino]-N-(4-formylphenyl)pyrimidine-4-carboxamide (Intermediate 24) and azetidine-3-carboxylic acid (Apollo), the title compound was obtained as a yellow solid after precipitation from DCM/MeOH.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399448B2
Source datasetuspto-grants-2013_03
ORD IDord-046b4fe262f046b89550cdd6b9052df6
Source noteuspto-grants-2013_03