HCID 59172056, compound → HCID 59172064, compound

Participants

Reaction Steps

A solution in EtOH (39 ml) of 10-benzyl-3-propionyl-3,10-diaza-bicyclo[4.3.1]decane obtained in Example 9 (2.40 g) was hydrogenated at 45 psi and at room temperature for 19 hours in the presence of Pd/C 10% (0.89 g). The mixture was filtered off on celite and the catalyst washed with EtOH. The solution was concentrated to obtain 1.60 g of a light oil corresponding to the compound 3-propionyl-3,10-diazabicy-clo[4.3.1]decane (10a).

Provenance & Evidence