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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1947034Generated: November 2, 2026

Iodoethane → HCID 69307229, compound

https://huagongshe.com/reaction/1947034

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 69307165HCID 69307165—
SolventWaterHCID 962—
SolventDimethylformamideHCID 6228—
ProductHCID 69307229HCID 6930722992.3%

Reaction Steps

N-[1-(2-Methylsulfanyl-pyrimidin-4-yl)-1H-indol-4-yl]-methanesulfonamide (0.4 g) in DMF (2 mL) was treated with K2CO3 (0.83 g) followed by EtI (0.2055 g), stirred at RT overnight, diluted with water, the solid filtered, washed with water and dried at 50° C. in vacuo overnight to yield N-ethyl-N-[1-(2-methylsulfanyl-pyrimidin-4-yl)-1H-indol-4-yl]-methane-sulfonamide (0.4 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399462B2
Source datasetuspto-grants-2013_03
ORD IDord-1f09d9f459b3432c92c445a298453493
Source noteuspto-grants-2013_03