m-Chloroperbenzoic acid → HCID 69309553, compound

Participants

Reaction Conditions

Reaction Steps

N-ethyl-N-[1-(2-methylsulfanyl-pyrimidin-4-yl)-1H-indol-4-yl]-methanesulfonamide (0.4 g) in CHCl3 (60 mL) was cooled to 0° C. and MCPBA (0.247 g) added and stirred at 0° C. for 5 h before quenching with 10% sodium thiosulfate solution. The organic layer was separated, dried over sodium sulfate, filtered, concentrated and purified on a column using 100% DCM to 15% MeOH/DCM to yield N-ethyl-N-[1-(2-methylsulfinyl-pyrimidin-4-yl)-1H-indol-4-yl]-methanesulfonamide (0.386 g).

Provenance & Evidence