Ammonium Acetate → HCID 68513590, compound

Participants

Reaction Steps

The desired compound was prepared in a manner similar to that described in Example 137 from 4-[1-(4-Chloro-benzoyl)-4-hydroxy-pyrrolidin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester in 99% yield. 1H-NMR (300 MHz, D2O): δ 2.75 (1H, m), 3.0 (1H, m), 3.15 (4H, m), 3.25 (3H, m), 3.3-3.5 (2H, m), 3.7 (1H, m), 3.9 (1H, m), 4.4 (1H, m), 7.35 (4H, dd). Retention Time (LC, method: ammonium acetate standard): 0.89 min. MS (M+H+): 310.

Provenance & Evidence