Ethyl Acetate → HCID 66893405, compound

Participants

Reaction Steps

A solution of the compound of Example 563 (250 mg, 0.46 mmol) and 4N hydrogen chloride ethyl acetate solution (0.114 mL, 0.46 mmol) in methanol (3.0 mL)-ethyl acetate (3.0 mL) was stirred at room temperature for 10 min. The reaction mixture was concentrated under reduced pressure, and the residue was recrystallized from methanol-diethyl ether to give the title compound (45 mg, 17%) as a white solid.

Provenance & Evidence