HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 50998716, compound → HCID 58235065, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 50998716 | HCID 50998716 | — |
| Reactant | 8-(1-bromoethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide hydrobromide | HCID 67103675 | — |
| Product | HCID 58235065 | HCID 58235065 | 36.1% |
Reaction Steps
3,4,5-trifluoro-N-methylaniline (197 mg, 1.22 mmol) was reacted with 8-(1-bromoethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide hydrobromide (150 mg, 0.31 mmol) using an analogous procedure to the one described in Example 3.03 to give N,N-dimethyl-8-(1-(methyl(3,4,5-trifluorophenyl)amino)ethyl)-2-morpholino-4-oxo-4H-chromene-6-carboxamide (54.0 mg, 36.1%) as a white solid. Mass Spectrum: M+H+ 490.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399460B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-b74ac2937857493db627125577e35377 |
| Source note | uspto-grants-2013_03 |