Sodium Carbonate → HCID 135923061, compound

HRID 1947446Notes

Reaction equation

HRID 1947446 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]3[CH:15]=[CH:14][C:13]([C:16]([NH:18][O:19][C:20](OCC)=[O:21])=[NH:17])=[CH:12][N:11]3[CH:25]=2)=[CH:4][CH:3]=1.C(=O)([O-])[O-].[Na+].[Na+]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]3[CH:15]=[CH:14][C:13]([C:16]4[NH:17][C:20](=[O:21])[O:19][N:18]=4)=[CH:12][N:11]3[CH:25]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 10340Sodium CarbonateHCID 178473664HCID 178473664, compound

Product 1

HCID 135923061HCID 135923061, compoundYield 14%

Procedure

The compound was synthesized by treatment of 2-(4-fluoro-phenyl)-N-ethoxycarbonyloxy-imidazo[1,2-a]pyridine-6-carboxamidine (example 60) with aqueous sodium carbonate. Yield: 14%. MS: M+H+=296.95.

Sources & evidence

ORD record
ord-823de65c54d44cbdb6e152fdf4dc4062
Source dataset
uspto-grants-2013_03
Patent number
US08399476B2

Reaction notes

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