HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-2-(4-nitrophenoxy)propanamide → 2-(4-Aminophenoxy)-2-methylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-2-(4-nitrophenoxy)propanamide | HCID 12321522 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(4-Aminophenoxy)-2-methylpropanamide | HCID 57562907 | — |
Reaction Steps
2-(4-Nitrophenoxy)-2-methylpropanamide was dissolved in methanol (50 mL) and to the solution was added 10% Pd—C (500 mg). The reaction mixture was reacted under hydrogen atmosphere (˜40 psi) for 1 h. The catalyst was filtered off over celite. The filtrate was evaporated to give 2-(4-aminophenoxy)-2-methylpropanamide as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399472B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-3fda6428167d40cda11914c9a213a5e6 |
| Source note | uspto-grants-2013_03 |