Tert-butyl 1-(4-nitrophenyl)-[4,4-bipiperidine]-1-carboxylate → HCID 59178880, compound

Participants

Reaction Steps

A suspension of the product of Example 12.29, Step 1 above (640 mg; 1.643 mmol) in an EtOH/EtOAc mixture (15 mL; 1:2 vol. ratio) was hydrogenated (35 psi) in the presence 10% Pd/C catalyst (150 mg) for 1 hr. The mixture was filtered through Celite and evaporated to afford the title compound as a gray solid.

Provenance & Evidence