HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propynamide → 2-[4-(Aminocarbonyl)-1H-1,2,3-triazol-1-yl]propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propynamide | HCID 101445 | — |
| Reactant | Tert-butyl 2-azidopropanate | HCID 86634922 | — |
| Product | 2-[4-(Aminocarbonyl)-1H-1,2,3-triazol-1-yl]propanoic acid | HCID 57907639 | — |
Reaction Steps
2-[4-(Aminocarbonyl)-1H-1,2,3-triazol-1-yl]propanoic acid was prepared from commercially available propiolamide and tert-butyl 2-azidopropanate using a procedure analogous to that used to prepare Intermediate 52. 1HNMR (500 MHz, CD3OD) δ: 8.48 (s, 1H), 5.50 (q, J=7.3 Hz, 1H), 1.85 (d, J=7.3 Hz, 3H). LC-MS: m/z (ES) 185 (MH)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399480B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-788c27e846544d2fbec2d01d234b19d4 |
| Source note | uspto-grants-2013_03 |